Post-doctoral Position in 3D Chromatin Architecture - Genova, Italia - Istituto Italiano di Tecnologia

Istituto Italiano di Tecnologia

Azienda verificata

Genova, Italia

3 settimane fa

Inviato da:

Piero Bianchi

Reclutatore di talenti per beBee

Descrizione

Post-doctoral position in 3D chromatin architecture and non-coding RNAs
Z)- Commitment & contract: collaboration contract_

WHO WE ARE

At IIT we work enthusiastically to develop human-centered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society.

Our Genoa headquarter is strictly inter-connected with our 11 centers around Italy and two outer-stations based in the US for a truly interdisciplinary experience.

YOUR TEAM

You will be working in a multicultural group, where computational scientists and molecular biologists collaborate, each with their own expertise, to carry out a scientific activity with a shared research goal.

We aim to understand how non-coding elements (DNA/RNA) and their epigenetic/epitranscriptomics modifications regulate 3D genome architecture and gene expression in stem cells and cancer models.

To address this question, we use cutting-edge chromatin conformation assays such as Hi-C, Hi-ChIP and Pore-C in conjunction with other -omics techniques (e.g. ChIP-seq, TT-seq, scRNA-seq) and in combination with CRISPR-based genetic and epigenetic engineering tools.

The final goal is to understand how ncRNAs can induce and/or maintain 3D promoter-enhancer contacts, which ultimately determines the transcriptional program that dictates stemness and tumorigenesis.

Within the team, your main responsibilities will be:

Perform experiments in the area of 3D chromatin conformation, stem cells, non-coding RNAs and epitranscriptomics.
Use advanced molecular biology techniques for the manipulation of chromatin, RNA, DNA and proteins.
Assist in generating preliminary data and figures for grant proposals
Supervise and mentor junior members of the team

WHAT WOULD MAKE YOU SHINE

A PhD in Biology including Molecular Biology, Biochemistry or Genetics
Previous experience in stem cell culture and advanced molecular biology techniques
Knowledge of NGS technologies, including but not limited to CHIPseq, RNAseq, ATACseq etc
A strong publication record
Excellent command in spoken and written English

EXTRA AWESOME

Experience in 3D chromatin conformation assays (e.g. Hi-C and Hi-ChIP etc)
Previous research experience in RNA biology (noncoding RNAs is a plus)
Ability to perform genomic and epigenomic editing techniques in stem cells using CRISPR(d)Cas technologies
Ability to work in a challenging and international environment
Ability to work independently and collaboratively in a highly interdisciplinary environment

COMPENSATION & BENEFITS

Competitive salary package for international standards
Private health care coverage
Wide range of staff discounts

WHAT'S IN FOR YOU?

An equal, inclusive and multicultural environment ready to welcome you with open arms. Discrimination is a big NO for us
We like collaboration and encourage you to mingle and discover what other people are up to in our labs
If paperwork is not your piece of cake, we got you There's a specialized team working to help you with that, especially during your relocation
If you are a start upper or a businessminded person, you will find some exceptionally gifted professionals ready to nurture and guide your attitude and aspirations.
If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and wellbeing of society
We stick to our values Integrity, courage, societal responsibility and inclusivity are the values we believe in They define us and our actions in our everyday life. They guide us to accomplish IIT mission

If you feel this tickles your appetite for change, do not hesitate and apply

Application's deadline:
October 31st
2023

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia._
Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security._

Primary Location GENOVA ERZELLI

Job Postdoc

Organization 3D Chromatin Conformation and RNA Genomics

Job Posting Aug 1, 2023, 7:29:55 AM