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Internship: Molecular Biology - Siena, Italia - GSK

GSK

Azienda verificata

Siena, Italia

1 mese fa

Inviato da:

Piero Bianchi

Reclutatore di talenti per beBee

StageSHIP

Descrizione

Site Name: Italy - Siena

Posted Date: Jul

Join our Internship Programme to Combat Diseases Together:

Objectives and Execution Methods

The intern will be part of the IT Molecular Biology & Bacteriology function, specifically the Antigen & Antibody Design and Expression group.

The intern will support the antigen expression platform, which will be expressed as recombinant proteins in _E. coli_.

In particular, they will be involved in the development and optimization of new systems for the expression of outer membrane proteins using molecular biology techniques and genetic engineering of Gram-negative bacteria.

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They will also be involved in all stages of work:

Collection of requests from various projects
Seed storage and clone registration in dedicated databases
Bacterial culture growth and verification of protein expression
Report writing

Skills the intern will develop through the internship experience

The intern will have the opportunity to learn the most advanced molecular biology techniques for protein expression in _E.

coli_, both through episomal expression and stable genomic integration.

The intern will explore all techniques applied to the antigen production process such as: generation of recombinant _E. coli_ strains, DNA manipulation, quantification of protein expression levels, small-scale purification.

They will also learn to use bioinformatics tools to evaluate the biophysical characteristics of antigens, such as amino acid composition, isoelectric point, hydrophobicity, and molecular weight, and tools for structural analysis and sequencing, all essential information to define the best approach to take during construct design and expression.

Duration: 1 year

Start Date: September 4 or 11, 2023

Why You?:

Basic Requirements:

Degree in Biotechnology, Molecular Biology, or similar.
One of the required qualifications is having developed university experience in the manipulation of _E. coli_ for the expression of recombinant proteins during thesis periods or other previous internships.
Preferably required: skills in generating _E. coli_ mutants (knockout and complementation).
Good written and oral English skills

Preferred Requirements:

Demonstrate being an enterprising and curious person.
Relational and teamwork skills

Let's do this**You'll find hints, tips, and guidance on our recruitment process on our website

We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as outlined in our Equal and Inclusive Treatment of Employees policy.

We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

You can learn more here.

GSK is a global biopharma company with a special purpose - to unite science, technology, and talent to combat diseases together - positively impacting the health of billions of individuals and delivering stronger, more sustainable shareholder returns - fostering an environment where people can thrive.

Our success depends on our people.

While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive.

We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as outlined in our Equal and Inclusive Treatment of Employees policy.

We're committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

GSK is an Equal Opportunity/Affirmative Action Employer.

All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status, or any other federal, state, or local protected class.

Important notice to Employment businesses/ Agencies

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment.

This capture of applicable transfers of value is necessary to ensure GSK's compliance with all federal and state US Transparency requirements.

For more information, please visit GS