Postdoctoral Position in Bioinformatic - Milano, Italia - Istituto Italiano di Tecnologia

Istituto Italiano di Tecnologia

Azienda verificata

Milano, Italia

3 settimane fa

Inviato da:

Piero Bianchi

Reclutatore di talenti per beBee

Descrizione

Postdoctoral position in Bioinformatic
E)

Project: Deciphering the impact of the MYC oncogene on the dynamics of RNA metabolism_
Commitment & contract: collaboration contract, 1 or 2 years _
Location: Milan_

WHO WE ARE

At IIT we work enthusiastically to develop humancentered Science and Technology to tackle some of the most pressing societal challenges of our times and transfer these technologies to the production system and society. Our Genoa headquarter is strictly interconnected with our 11 centers around Italy and two outerstations based in the US for a truly interdisciplinary experience.

YOUR TEAM
You will be working in a multicultural and multi-disciplinary group, where molecular biologists and computational scientists
_ _collaborate, each with their own expertise, to carry out common research.

The group has recently developed a novel method able to decipher how RNA abundance is dynamically controlled, at the level of different cellular compartments, through the coordinated action of various transcriptional machineries. In particular the method is able to quantify the efficiency of RNA synthesis, splicing, export, translation and degradation. The research focuses on understanding how MYC, an important transcription factor and oncogene, shapes the dynamics of RNA metabolism by impacting these steps of the RNA life cycle. This project relies on mathematical modelling methods established in the group and Nanopore sequencing of native RNA.
Within the team, your main responsibilities will be:
Analyzing second (Illumina short-reads) and third (Nanopore long-reads) generation high-throughput sequencing data
Taking advantage of available systems for the acute perturbation of MYC, to decipher how it impacts the dynamics of RNA metabolism
Dissect the contribution of RNA modifications in the context of aberrant gene expression programs controlled by the MYC oncogene
Closely interact with the experimental scientists for the interpretation of the results and the design of followup experiments
Collaborate with other group members on exciting projects focused on studying how RNA dynamics and RNA modifications shape RNA fate and lead to cancer

WHAT WOULD MAKE YOU SHINE

A PhD in Bioinformatics or similar disciplines
Documented experience on the analysis of highthroughput sequencing data
Knowledge of R / Bioconductor
A good publication track record
The ability to properly report, organize and publish research data
Documented experience in coaching junior scientists
Good command in spoken and written English

EXTRA AWESOME

Quantitative background, such as physics or engineering
Knowledge or strong interest in RNA dynamics
Experience on the analysis of Nanopore sequencing data
Experience on the analysis of epitranscriptional data
Good communication skills
Strong problemsolving attitude
High motivation to lear
Spirit of innovation and creativity
Good in time and priority management
Ability to work in a challenging and international environment
Ability to work independently and collaboratively in a highly interdisciplinary environment

COMPENSATION & BENEFITS

Competitive salary package for international standards
Private health care coverage
Wide range of staff discounts

WHAT'S IN FOR YOU?

An equal, inclusive and multicultural environment ready to welcome you with open arms. Discrimination is a big NO for us
We like contamination and encourage you to mingle and discover what other people are up to in our labs
If paperwork is not your piece of cake, we got you There's a specialized team working to help you with that, especially during your relocation
If you are a startupper or a businessminded person, you will find some exceptionally gifted professionals ready to nurture and guide your attitude and aspirations.
If you want your work to have a real impact, in IIT you will find an innovative and stimulating culture that drives our mission to contribute to the improvement and wellbeing of society
We stick to our values Integrity, courage, societal responsibility and inclusivity are the values we believe in They define us and our actions in our everyday life. They guide us to accomplish IIT mission

If you feel this tickles your appetite for change, do not hesitate and apply

Application's deadline:
December 15th
2023

We inform you that the information you provide will be used solely for the purposes of evaluating and selecting professional profiles in order to meet the requirements of Istituto Italiano di Tecnologia._
Your data will be processed by Istituto Italiano di Tecnologia, based in Genoa, Via Morego 30, acting as Data Controller, in compliance with the rules on protection of personal data, including those related to data security._

Primary Location MILANO SEMM

Job Postdoc

Organization Istituto Italiano di Tecnologia

Job Posting Nov 20, 2023, 10:04