Mrna Scientist - Monza, Italia - Thermo Fisher Scientific

Thermo Fisher Scientific

Azienda verificata

Monza, Italia

5 giorni fa

Inviato da:

Piero Bianchi

Reclutatore di talenti per beBee

Descrizione

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of more than $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer.

Whether our customers are accelerating life sciences research, solving complex analytical challenges, growing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them.

Our distributed team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD.

The Scientist will work within the mRNA Process & Analytical Method Development Group and will contribute to the process & analytical methods' development, improvements, and transfer of mRNA products to cGMP and QC groups.

Key responsibilities will include hands-on laboratory development, mRNA process characterization & development for new products, process improvements, and document drafting.

Responsibilities:

Handson experience in DNA/RNA extraction, gene expression assays, qRTPCR, primer design, and gene expression analysis is critical.
Experience in developing robust and scalable downstream processes to purify nucleic acids with liquid chromatography (FPLC) is highly desirable.

- should also design, implement, and fix experiments to optimize assay performance, and provide clear and concise project status updates to internal and external stakeholders.
- should be able to perform routine bench work under limited supervision, prioritize responsibilities effectively, and complete assignments on time.
- should also be able to analyze, interpret, and present results to project teams, and write technical reports.

Maintaining domain expertise in new technologies and scientific literature is critical to constantly drive innovation.

Qualifications:

Requirements:

Expert level understanding and hands on experience with next generation sequencing (NGS) assays and workflows.
Expert level understanding of standard molecular biology techniques including PCR, qPCR, cloning, nucleic acid extraction and quantification, and invitro transcription.
Experience with NGS assay development.
Experienced with DNA and RNA sample processing and sample stabilization procedures.
Experience in process development for therapeutics with standard downstream purification techniques, including depth filtration, FPLC and Tangential flow filtration (TFF) is highly desirable.
Familiarity with the process development of mRNA products would be a plus.
Experience with GLP and GMP compliance and manufacturing preferred.
Experience writing content for documentation, including SOPs, work instructions, technical protocols and reports, and technical presentations.
A high level of commitment and a track record of quality work, with attention to detail.
Capable of presenting the work clearly among the team.
Ability to multitask and prioritize to meet important deadlines.
Ability to respond quickly to constantly evolving priorities.
A selfstarter and great teammate.
Excellent written and spoken English.

Thermo Fisher Scientific is an Equal Opportunity Employer.

All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status.

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